Securus Benefits

Experience the success of Securus

Our ingredients are based upon the extensive research conducted by the National Institutes of Health and independent universities.  In fact, at present these are the only ingredients validated through research to be effective.

Dr. Mark Anderson, PhD is the founder of Nevada Center for Behavior Therapy (NVCBT), a unique practice that specializes in the treatment of anxiety and mood disorders. He found that certain herbal, vitamin and amino acid interventions were consistently shown to reduce anxiety. These ingredients are the foundation of Securus. Securus is the natural anxiety relief supplement that works quickly, with virtually no side effects. It harnesses the power of natural interventions to provide the sense of calm everyone deserves.

Manufactured in the USA, the ingredients in Securus have all been shown to have strong anti-anxiety effects and are non-addictive. Securus will promote a feeling of wellness and calm quickly (in some cases as fast as 20 minutes) that is long lasting. When you purchase Securus, you will receive a bottle of 90 capsules. You may take Securus daily or on an as needed basis.

 

INGREDIENTS

Kava Kava Info

Kava-kava (aka – Piper methysticum) has been used by Pacific Islanders as a ceremonial drink, social beverage, and therapeutic elixir for relaxation and anti-anxiety for thousands of years. However, it wasn’t until 1995 that Kava began being used in the United States for its relaxation properties, and scientific assessment of Kava began in earnest about this time as well. According to research by the nationally-known Psychiatrist, Dr. Hyla Cass, (click here for more on Dr. Cass: http://www.cassmd.com/about/) Kava has been shown to interact with the limbic system (the emotional center of the brain) to increase relaxation. Perhaps a recent article written by faculty at Vanderbilt University summarizes it the best: “Kava-Kava appears to be a reliable herbal remedy that could be useful in the reduction of stress and anxiety. By providing a safer and beneficial alternative to prescription psychiatric medications, Kava-Kava could be the solution to today’s problems of stress and anxiety.” (Reference: http://www.vanderbilt.edu/AnS/psychology/health_psychology/kava.htm)

Kava Kava Research

The use of Kava-Kava in the treatment of anxiety has been studied extensively, and has research support mentioned in several Cochrane Collaboration summaries. A recent 2010 Cochrane Collaboration study (PMID: 12535473) investigating the use of Kava compared to placebo found that “Compared with placebo, kava extract is an effective symptomatic treatment for anxiety.” All 12 research publications that were included in this Cochrane study were randomized, double-blind studies and other design types were excluded. Based on a group size of 700, the Hamilton Anxiety (HAM-A) rating scores of those in the Kava group decreased significantly more (p<.05) than those in the Placebo group.

A Cochrane Collaboration study conducted in 2009 (PMID: 16856115) evaluating 5-HT1A medications, known as Azapirones, in the treatment of GAD revealed that Kava is equally effective at treating GAD as the medications. This conclusion was based on 36 clinical trials with 5908 participants.

A 2010 meta-analysis and overview article (PMID: 20493333) that discusses the use of complementary and alternative medicine (CAM) intervention in all psychological areas found that “kava has high-quality evidence for use in the treatment of anxiety disorders” and found that kava can be used safely and effectively for at least 24 weeks.

A 2009 biological investigation (PMID: 19865069) into Kava determined that it inhibits both norephinephrine uptake and sodium and potassium channels, which leads to anxiolytic effects. A separate 2009 meta-analysis investigation into the use of kava in treating anxiety disorders (PMID: 19614563) again confirmed its efficacy.

In all, 11 investigations that are either Cochrane Collaboration studies, meta analyses, or high-sample double blind studies have shown kava to be effective in addressing anxiety: (PMIDs: 12535473,16856115,20493333,19865069,19614563,19029875, 10711131,17853630, 20929532, 19430766, 21073405).

GABA Information

Gaba Research is ongoing...GABA technically stands tor Gamma-Aminobutyric acid, which is a neurotransmitter in the brain. GABA acts on inhibitory synapses in the brain by binding to specific receptors in the plasma membrane of both presynaptic and postsynaptic neuronal processes. In other words GABA helps inhibit, or stop, other reactions from occurring, including anxiety. Consistent and detailed research has shown that substances that increase GABA in the system have relaxing, anti-anxiety effects (References: PMID 16377242, PMID: 11583788, PMID: 12946638, PMID: 16971751). As an added benefit, research also suggests that GABA helps with immunity.

GABA Research

Consistent and detailed research has shown that substances that increase GABA in the system have relaxing, anti-anxiety effects. For example, a 2006 study (PMID: 16971751) found that oral administration of GABA increases alpha waves and decreases beta waves in the brain, compared to placebo or L-theanine. Alpha waves predominantly originate from the occipital lobe during wakeful relaxation, while beta waves are often associated with active, busy, or anxious thinking. This study therefore suggests that GABA both increases the positive feelings of relaxation and simultaneously decreases the negative feelings of anxiety.

In a second study published in the same paper, the authors found that GABA decreases anxiety in real-world fearful events. The subjects in the experiment were extremely afraid of heights, and volunteered to cross a high suspension bridge. Half were given placebo, and half were given GABA. Those in the GABA group were shown to have significantly higher levels of Immunoglobulin A which is a class of antibodies that protects the body from infections.

A 2009 study (PMID: 19865069) found that oral administration of GABA was absorbed and used by the body, and· was shown to increase available GABA levels inside the body. This study was conducted to address the concern that orally administered GABA was simply excreted out of the body, and not actually used by it.

A 2010 overview paper (PMID: 20655491) that looked at the role of GABA in anxiety and depression states: “A clear link between GABA receptors and anxiety has long been established” and that increasing GABA decreases anxiety. Most fast-acting anti-anxiety medications (such as Xanax, Klonopin or Valium) all target the GABA system for this reason. Orally administered GABA seems to work as fast as these medications, with effects being seen in 20-60 minutes.

Since 2006, five different studies assessing the role of GABA in anxiety support its usefulness and anxiolytic effects (PMIDs: 16971751, 19865069, 20655491, 20614802, and 19346282).

Bacopa Information

Bacopa InfoBacopa Monnieri (aka Coastal Waterhyssop, Brahmi, Thyme-leafed gratiola, Water hyssop) is an herbal plant whose habitat includes wetlands and muddy shores.

Found mostly in India, Sri Lanka and Nepal, it can also be found domestically growing in places like Florida or Hawaii. While it has a long history of being used to treat epilepsy and asthma, it was only recently that rigorous scientific study has shown that it has anti-anxiety effects as well (Reference: PMID: 18611150, PMID: 16428031 ).

Bacopa Research

It wasn’t until relatively recently that assessments began to determine if Bacopa Monnieri had anti-anxiety affects. The earliest examination of Bacopa Monnieri’s effect on anxiety appears to have taken place in 1980 (Singh RH, Singh L. Studies on the anti-anxiety effect of the Medyha Rasayana drug, Brahmi (Bacopa monniera Wettst.) – Part l. J Res Ayur Siddha 1980; 1: 133-148.). This study suggested the powerful effect of Bacopa, and found that the oral administration of it“resulted in a significant decrease in anxiety symptoms, level of anxiety, level of disability, and mental fatigue, and an increase in immediate memory span.”

Other early testing of Bacopa Monnieri occurred in 1998 (Bhattacharya SK, Ghosal S. Anxiolytic activity of a standardized extract of Bacopa monniera in an experimental study. Phytomedicine 1998;5:77-82.). This investigation found that Bacopa Monnieri “exerted anxiolytic activity comparable to Lorazepam, a common benzodiazepine anxiolytic drug.” A follow-up study performed in 2002 (PMID: 12093601) with a small sample of people determined that Bacopa increased memory functions in individuals who took it, and had some small degree of effect on anxiety. Building on this early success, another 2002 (PMID: 2410544) study examined the neurobiology of Bacopa and found that higher doses than previously given would indeed have anti-effects. However, this experiment was based on animal testing and it was uncertain if the positive results would be seen in humans as well.

It wasn’t until 2008 that a well-structured double blind study was conducted to assess the affect of Bacopa in humans (PMID:18611150). This study found that when people took 300mg/day of Bacopa, their anxiety rating scored decreased significantly when compared to the placebo group. Most interestingly, both short term anxiety and long-term anxiety decreased with the administration of Bacopa. This means that not only did the Bacopa Monnieri alleviate acute anxiety, it actually prevented and decreased chronic long-term anxiety.

Further 2009 animal studies (PMID: 19700373) determined that Bacopa affects the neurobiology of the hippocampus, which is often associated with anxiety. Specifically, it was shown to create an “upregulation of 5-HT(2C) receptors.” It has been shown that in anxiety a neurochemical known as Serotonin is low, and the receptors for it are few. The scientific name for Serotonin is 5-HT. Therefore, this 2009 study showed that Bacopa increases Serotonin, which has been shown to decrease anxiety. This is why the class of pharmaceutical drugs that are used to prevent anxiety (such as Lexapro, Zoloft, or Paxil) is designed to target Serotonin and increase it. This 2009 study suggests that Bacopa Monnieri can increase serotonin – no artificial medication required.

Further studies performed in 2010 and 2011 (PMIDs: 9944749, 20850955) both continue to support the positive anxiety affects of Bacopa Monnieri. A search of the PubMed database has found that since 1982, 161 studies have been conducted examining the affect of Bacopa, and it has consistent data supporting its use in anti-anxiety efforts.

Passionflower Information

Passionflower is also known as Passiflora, and is a genus of about 500 species of flowering plants.Passionflower is also known as Passiflora, and is a genus of about 500 species of flowering plants. They are mostly vines, with some being shrubs, and a few species being herbaceous (a plant classified as an herb). Passionflower has a long history of use by Native Americans, and European Colonists adopted its use for anti-anxiety and insomnia treatments. Passionflower has many compounds that can be found within it, but the presence of it is most important in terms of anxiety, as it has confirmed anti-anxiety properties (References: PMID: 17966676, PMID: 7906886, ISBN 0-89529-869-4). A recent study has also shown that Passionflower has been as effective as the prescription drug oxazepam (brand name Serax) in reducing anxiety (Reference: PMID: 11679026).

Passionflower Research

A recent Cochrane Collaboration study conducted in 2007 (PMID: 17253512) has found evidence that Passionflower and benzodiazepines are equally effective in the treatment of anxiety disorders. Benzodiazepine medications are first-line prescription medications, and include medications such as Xanax, Klonopin, and Valium. Similarly, a 2010 meta-analysis (PMID: 20929532) based on 2619 subjects found that “strong evidence exists for the use of herbal supplements containing extracts of passionflower…as treatments for anxiety symptoms and disorders.” The article goes on to state that these positive effects can be observed “without the risk of serious side effects.”

A 2009 study (PMID: 19123457) conducted by researchers at the Depression and Anxiety Disorders Research Program in Cambridge, Massachusetts again indicates that passionflower can play a role in anxiety treatment, though the authors emphasize a need for more double-blind research. However, a biological study conducted in 2010 (PMID: 21089181) which investigated passionflower found that it works through the GABA system in the body, which is a well-established relaxation intervention. Overall, eight Cochrane Collaboration, meta-analyses, or high-sample double blind studies have supported the use of Passionflower in the treatment of Anxiety: (PMIDs: 17253512, 19123457, 20929532, 17562566, 12391715, 12244887, 10711131, and 21089181).

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